HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage.

The role of the E6 oncoprotein from high-risk members of the α human papillomavirus genus in anogenital cancer has been well established. However, far less is known about the E6 protein from the β human papillomavirus genus (β-HPVs). Some β-HPVs potentially play a role in non-melanoma skin cancer de...

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Bibliographic Details
Main Authors: Nicholas A Wallace, Kristin Robinson, Heather L Howie, Denise A Galloway
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3395675?pdf=render