Control of lysogeny and antiphage defense by a prophage-encoded kinase-phosphatase module

Abstract The filamentous ‘Pf’ bacteriophages of Pseudomonas aeruginosa play roles in biofilm formation and virulence, but mechanisms governing Pf prophage activation in biofilms are unclear. Here, we identify a prophage regulatory module, KKP (kinase-kinase-phosphatase), that controls virion product...

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Bibliographic Details
Main Authors: Yunxue Guo, Kaihao Tang, Brandon Sit, Jiayu Gu, Ran Chen, Xinqi Shao, Shituan Lin, Zixian Huang, Zhaolong Nie, Jianzhong Lin, Xiaoxiao Liu, Weiquan Wang, Xinyu Gao, Tianlang Liu, Fei Liu, Hongbo R. Luo, Matthew K. Waldor, Xiaoxue Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51617-x