Mouse embryonic stem cells resist c-Jun induced differentiation when in suspension
The oncogene c-Jun plays a key role in development and cancer. Yet, its role in cell fate decision remains poorly understood at the molecular level. Here we report that c-Jun confers different fate decisions upon mouse embryonic stem cells (mESCs) in adhesion vs suspension culture. We developed a Te...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
SpringerOpen
2018-09-01
|
Series: | Cell Regeneration |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2045976918300038 |