Mouse embryonic stem cells resist c-Jun induced differentiation when in suspension

The oncogene c-Jun plays a key role in development and cancer. Yet, its role in cell fate decision remains poorly understood at the molecular level. Here we report that c-Jun confers different fate decisions upon mouse embryonic stem cells (mESCs) in adhesion vs suspension culture. We developed a Te...

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Bibliographic Details
Main Authors: Bo Wang, Dongwei Li, Jiekai Chen, Jing Liu, Duanqing Pei
Format: Article
Language:English
Published: SpringerOpen 2018-09-01
Series:Cell Regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2045976918300038