RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31

Abstract RNF31 (HOIP), RBCK1 (HOIL-1L), and SHARPIN are subunits of the linear ubiquitin chain assembly complex. Their function and specific molecular mechanisms in hepatocellular carcinoma (HCC) have not been reported previously. Here, we investigated the role of RNF31 and RBCK1 in HCC. We showed t...

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Bibliographic Details
Main Authors: Xijun Chen, Qing Ye, Wenxiu Zhao, Xiaoqin Chi, Chengrong Xie, Xiaomin Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01126-x