Effect of the T-domain on intracellular transport of diphtheria toxin

Subunit B of diphtheria toxin (DT), which consists of two domains: R (receptor-binding) and T (transmembrane), plays an important role in toxin-receptor binding on the cell-targets and in transportation of catalytic subunit A to the cell cytosol. Recombinant analogues of the subunit B are promising...

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Bibliographic Details
Main Authors: А. J. Labyntsev, D. V. Kolybo, E. S. Yurchenko, A. A. Kaberniuk, N. V. Korotkevych, S. V. Komisarenko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2014-06-01
Series:The Ukrainian Biochemical Journal
Subjects:
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Labyntsev_3_14.pdf