Senescence-specific molecular subtypes stratify the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer

Senescence-specific molecular subtypes stratify the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer

Abstract Background Bladder cancer (BLCA) is notably associated with advanced age, characterized by its high incidence and mortality among the elderly. Despite promising advancements in models that amalgamate molecular subtypes with treatment and prognostic outcomes, the considerable heterogeneity i...

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Bibliographic Details
Main Authors: Luzhe Yan, Haisu Liang, Tiezheng Qi, Dingshan Deng, Jinhui Liu, Yunbo He, Jinbo Chen, Benyi Fan, Yiyan Yao, Kun Wang, Xiongbing Zu, Minfeng Chen, Yuanqing Dai, Jiao Hu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Bladder cancer
Cellular senescence
Tumor microenvironment
Molecular subtype
Precision medicine
Online Access:https://doi.org/10.1186/s12885-025-13698-9

Internet

https://doi.org/10.1186/s12885-025-13698-9

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