In Silico Screening and Molecular Dynamics Simulation Studies in the Identification of Natural Compound Inhibitors Targeting the Human Norovirus RdRp Protein to Fight Gastroenteritis

In Silico Screening and Molecular Dynamics Simulation Studies in the Identification of Natural Compound Inhibitors Targeting the Human Norovirus RdRp Protein to Fight Gastroenteritis

Norovirus (HNoV) is a leading cause of gastroenteritis globally, and there are currently no treatment options or vaccines available to combat it. RNA-dependent RNA polymerase (RdRp), one of the viral proteins that direct viral replication, is a feasible target for therapeutic development. Despite th...

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Bibliographic Details
Main Authors: Rami J. Obaid, Alaa Shafie, M. Shaheer Malik, Munirah M. Al-Rooqi, Ziad Moussa, Osama Abdulaziz, Abdulelah Aljuaid, Mamdouh Allahyani, Mazen Almehmadi, Farah Anjum, Saleh A. Ahmed
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Norovirus
gastroenteritis
RdRp
viral replication
natural compounds
Online Access:https://www.mdpi.com/1422-0067/24/5/5003

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https://www.mdpi.com/1422-0067/24/5/5003

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