Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji–Trost coupling
The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint urea-type substrate enables the facile preparatio...
Main Authors: | Sebastian Bretzke, Stephan Scheeff, Felicitas Vollmeyer, Friederike Eberhagen, Frank Rominger, Dirk Menche |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2016-06-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.12.107 |
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