Crosstalk between ROCK1 and PYROXD1 regulates CAFs activation and promotes laryngeal squamous cell carcinoma metastasis

Crosstalk between ROCK1 and PYROXD1 regulates CAFs activation and promotes laryngeal squamous cell carcinoma metastasis

Abstract We previously found that the Rho-associated kinase 1 (ROCK1) activated Cancer-associated fibroblasts (CAFs) to promote LSCC metastasis. Accumulating evidence indicates that pyridine nucleotide-disulfide oxidoreductase domain 1 (PYROXD1) is an oncogene; however, the crosstalk between ROCK1 a...

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Bibliographic Details
Main Authors: Liyun Yang, Peipei Qiao, Jianwei Zhang, Xiaoping Chen, An Hu, Shuixian Huang
Format: Article
Language:English
Published: Springer 2022-11-01
Series:Discover Oncology
Subjects:
PYROXD1
ROCK1
CAFs activation
Metastasis
LSCC
Online Access:https://doi.org/10.1007/s12672-022-00578-y

Internet

https://doi.org/10.1007/s12672-022-00578-y

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