The antipsychotic drug sulpiride in the ventral pallidum paradoxically impairs learning and induces place preference

The antipsychotic drug sulpiride in the ventral pallidum paradoxically impairs learning and induces place preference

Abstract Sulpiride, as a D2-like dopamine (DA) receptor (D2R) antagonist, is an important antipsychotic drug in the treatment of schizophrenia. Recently, we have shown that the activation of D2Rs in the ventral pallidum (VP) modulates the activity of the ventral tegmental area (VTA) DAergic neurons....

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Bibliographic Details
Main Authors: Daniella Dusa, Tamás Ollmann, Veronika Kállai, László Lénárd, Erika Kertes, Beáta Berta, Ádám Szabó, Kristóf László, Rita Gálosi, Olga Zagoracz, Zoltán Karádi, László Péczely
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23450-z

Internet

https://doi.org/10.1038/s41598-022-23450-z

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