Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy

Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy

Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of cisplatin, carboplatin and oxaliplatin by coupling via amide bonds to...

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Bibliographic Details
Main Authors: Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S. Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D. Mellor, David G. Workman, Michael A. Jakupec, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Mathea S. Galanski, Bernhard K. Keppler
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
platinum(IV) complexes
quaternary ammonium glycol chitosan (GCPQ)
anticancer
drug delivery
Online Access:https://www.mdpi.com/1424-8247/16/7/1027

Internet

https://www.mdpi.com/1424-8247/16/7/1027

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