The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells

The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells

ABSTRACT Contact-dependent hemolysins are virulence factors in a number of human pathogens, including Helicobacter pylori, Rickettsia typhi, Bartonella bacilliformis, Mycobacterium tuberculosis, entero-invasive Escherichia coli, and Shigella. Here we demonstrate that Neisseria gonorrhoeae produces a...

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Bibliographic Details
Main Authors: Michael A. Apicella, Jennifer L. Edwards, Margaret R. Ketterer, David S. Weiss, Yuan Zhang, Freda E.-C. Jen, Michael P. Jennings
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
Subjects:
Neisseria gonorrhoeae
phospholipase A
neutrophils
cervical epithelial cells
hemolysis
gonorrhea
Online Access:https://journals.asm.org/doi/10.1128/mbio.02425-24

Internet

https://journals.asm.org/doi/10.1128/mbio.02425-24

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