Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Reinstatement of Cocaine-Mediated Conditioned Place Preference in Mice

Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Reinstatement of Cocaine-Mediated Conditioned Place Preference in Mice

A high percentage of relapse to compulsive cocaine-taking and cocaine-seeking behaviors following abstinence constitutes a major obstacle to the clinical treatment of cocaine addiction. Thus, there is a substantial need to develop effective pharmacotherapies for the prevention of cocaine relapse. Th...

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Bibliographic Details
Main Authors: Changliang Zhu, Lei Wang, Jiangwei Ding, Hailiang Li, Din Wan, Yangyang Sun, Baorui Guo, Zhenquan He, Xiaofan Ren, Shucai Jiang, Caibing Gao, Hua Guo, Tao Sun, Feng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
cocaine
reinstatement
exendin-4
pretreatment
nuclear factor κβ
conditioned place preference
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.769664/full

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https://www.frontiersin.org/articles/10.3389/fnbeh.2021.769664/full

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