Identification of RUNX1T1 as a potential epigenetic modifier in small‐cell lung cancer

Identification of RUNX1T1 as a potential epigenetic modifier in small‐cell lung cancer

Small‐cell lung cancer (SCLC) can be subgrouped into common ‘pure’ and rare ‘combined’ SCLC (c‐SCLC). c‐SCLC features a mixed tumor histology of both SCLC and non–small‐cell lung cancer (NSCLC). We performed targeted exome sequencing on 90 patients with SCLC, including two with c‐SCLC, and discovere...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Tian He, Gary Wildey, Karen McColl, Alyssa Savadelis, Kyle Spainhower, Cassidy McColl, Adam Kresak, Aik Choon Tan, Michael Yang, Ata Abbas, Afshin Dowlati
Format: Artykuł
Język:English
Wydane: Wiley 2021-01-01
Seria:Molecular Oncology
Hasła przedmiotowe:
E2F pathway
epigenetics
exome sequencing
RUNX1T1
small‐cell lung cancer
Dostęp online:https://doi.org/10.1002/1878-0261.12829

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