DNA methylation and histone post-translational modification stability in post-mortem brain tissue

Abstract Background Epigenetic (including DNA and histone) modifications occur in a variety of neurological disorders. If epigenetic features of brain autopsy material are to be studied, it is critical to understand the post-mortem stability of the modifications. Methods Pig and mouse brain tissue w...

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Bibliographic Details
Main Authors: Jessica S. Jarmasz, Hannah Stirton, James R. Davie, Marc R. Del Bigio
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13148-018-0596-7