Functions and regulatory mechanisms of resting hematopoietic stem cells: a promising targeted therapeutic strategy

Functions and regulatory mechanisms of resting hematopoietic stem cells: a promising targeted therapeutic strategy

Abstract Hematopoietic stem cells (HSCs) are the common and essential precursors of all blood cells, including immune cells, and they are responsible for the lifelong maintenance and damage repair of blood tissue homeostasis. The vast majority (> 95%) of HSCs are in a resting state under physiolo...

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Bibliographic Details
Main Authors: Xinyu Tang, Zhenzhen Wang, Jingyi Wang, Siyuan Cui, Ruirong Xu, Yan Wang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Hematopoietic stem cells
Resting
Self-replication
Differentiation
Regulatory mechanism
Hemopathy
Online Access:https://doi.org/10.1186/s13287-023-03316-5

Internet

https://doi.org/10.1186/s13287-023-03316-5

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