Zerumbone reduces TLR2 stimulation-induced M1 macrophage polarization pattern via upregulation of Nrf-2 expression in murine macrophages

Zerumbone reduces TLR2 stimulation-induced M1 macrophage polarization pattern via upregulation of Nrf-2 expression in murine macrophages

Hyperuricemia contributes significantly to gout arthritis pathogenesis, which promotes urate crystal deposition in the joints and activates joint-resident macrophages and circulating monocytes to initiate a state of inflammatory arthritis. In the joint, macrophages have an immune defense role where...

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Bibliographic Details
Main Authors: Marwa Qadri, Zenat Khired, Reem Alaqi, Sandy Elsayed, Abdulaziz Alarifi, Rayan Ahmed, Hussain Alhamami, Amani Khardali, Walaa Hakami
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Saudi Pharmaceutical Journal
Subjects:
Hyperuricemia
Gout
sUA
TLR2
Macrophages
Polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016424000069

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http://www.sciencedirect.com/science/article/pii/S1319016424000069

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