Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

Proton-pump inhibitors (PPIs), frequently prescribed to lower gastric acid secretion, often exert an effect on the absorption of co-medicated drug products. A previous study showed decreased plasma levels of the lipophilic drug ritonavir after co-administration with the PPI Nexium (40 mg esomeprazol...

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Detalhes bibliográficos
Main Authors: Tom de Waal, Jari Rubbens, Michael Grimm, Vincent Vandecaveye, Jan Tack, Werner Weitschies, Joachim Brouwers, Patrick Augustijns
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2020-07-01
Colecção:Pharmaceutics
Assuntos:
MRI
PPI effect
ritonavir
gastric fluid volume
intestinal fluid volume
drug absorption
Acesso em linha:https://www.mdpi.com/1999-4923/12/7/670

Internet

https://www.mdpi.com/1999-4923/12/7/670

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