Hypoxia-ameliorated photothermal manganese dioxide nanoplatform for reversing doxorubicin resistance

Hypoxia-ameliorated photothermal manganese dioxide nanoplatform for reversing doxorubicin resistance

Drug resistance is a huge hurdle in tumor therapy. Tumor hypoxia contributes to chemotherapy resistance by inducing the hypoxia-inducible factor-1α (HIF-1α) pathway. To reduce tumor hypoxia, novel approaches have been devised, providing significant importance to reverse therapeutic resistance and im...

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Bibliographic Details
Main Authors: Zhenzhen Chen, Zhihong Liu, Qian Zhang, Sheng Huang, Zaizhong Zhang, Xianquan Feng, Lingjun Zeng, Ding Lin, Lie Wang, Hongtao Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
drug resistance
hypoxia
photothermal-manganese dioxide
doxorubicin
tumor microenvironment response
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1133011/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1133011/full

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