Tropomyosin 3 (TPM3) function in skeletal muscle and in myopathy

Abstract The tropomyosin genes (TPM1-4) contribute to the functional diversity of skeletal muscle fibers. Since its discovery in 1988, the TPM3 gene has been recognized as an indispensable regulator of muscle contraction in slow muscle fibers. Recent advances suggest that TPM3 isoforms hold more ext...

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Bibliographic Details
Main Authors: Matthias R. Lambert, Emanuela Gussoni
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Skeletal Muscle
Subjects:
Online Access:https://doi.org/10.1186/s13395-023-00327-x