Selecting single cell clustering parameter values using subsampling-based robustness metrics
Abstract Background Generating and analysing single-cell data has become a widespread approach to examine tissue heterogeneity, and numerous algorithms exist for clustering these datasets to identify putative cell types with shared transcriptomic signatures. However, many of these clustering workflo...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-03957-4 |