Skin Mast Cell-Driven Ceramides Drive Early Apoptosis in Pre-Symptomatic Eczema in Mice

Skin Mast Cell-Driven Ceramides Drive Early Apoptosis in Pre-Symptomatic Eczema in Mice

Atopic dermatitis (AD or eczema) is the most common chronic inflammatory skin disorder worldwide. Ceramides (Cer) maintain skin barrier functions, which are disrupted in lesional skin of AD patients. However, Cer status during the pre-lesional phase of AD is not well defined. Using a variation of hu...

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Bibliographic Details
Main Authors: Piper A. Robida, Alena P. Chumanevich, Alexa Orr Gandy, John W. Fuseler, Prakash Nagarkatti, Mitzi Nagarkatti, Carole A. Oskeritzian
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
fluorescence microscopy
gene expression
immunology
inflammation
endoplasmic reticulum
Online Access:https://www.mdpi.com/1422-0067/22/15/7851

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https://www.mdpi.com/1422-0067/22/15/7851

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