N-benzyl-N-methyldecan-1-amine, derived from garlic, and its derivative alleviate 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice

N-benzyl-N-methyldecan-1-amine, derived from garlic, and its derivative alleviate 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice

Abstract Given the intricate etiology and pathogenesis of atopic dermatitis (AD), the complete cure of AD remains challenging. This study aimed to investigate if topically applying N-benzyl-N-methyldecan-1-amine (BMDA), derived from garlic, and its derivative [decyl-(4-methoxy-benzyl)-methyl-1-amine...

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Bibliographic Details
Main Authors: Ji Eun Kim, Phatcharaporn Budluang, Jumin Park, Kon Ho Lee, Sirichatnach Pakdeepromma, Chutima Kaewpiboon, Ho Young Kang, Dae Youn Hwang, Young-Hwa Chung
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
N-benzyl-N-methyldecan-1-amine
2,4-Dinitrochlorobenzene
Atopic dermatitis
Inflammation
Mast cells
IgE titer
Online Access:https://doi.org/10.1038/s41598-024-56496-2

Internet

https://doi.org/10.1038/s41598-024-56496-2

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