Catalytic stereodivergent allylic alkylation of 2-acylimidazoles for natural product synthesis

Abstract The stereocontrolled allylic alkylation of carbonyl compounds with the goal of producing the full range of stereoisomers presents an effective approach for increasing the productivity of collective natural product synthesis and the creation of chiral molecule libraries for drug exploration....

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Bibliographic Details
Main Authors: Ruimin Lu, Qinglin Zhang, Chang Guo
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43986-6