Lynch syndrome pre-screening and comprehensive characterization in a multi-center large cohort of Chinese patients with colorectal cancer

Lynch syndrome pre-screening and comprehensive characterization in a multi-center large cohort of Chinese patients with colorectal cancer

Objective: Lynch syndrome (LS) pre-screening methods remain under-investigated in colorectal cancers (CRCs) in Asia. Here, we aimed to systematically investigate LS pre-screening and comprehensively characterize LS CRCs. Methods: Microsatellite instability (MSI) and germline variants of DNA mismatch...

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Bibliographic Details
Main Authors: Yan Li, Lihong Fan, Jianming Zheng, Xiu Nie, Yu Sun, Qin Feng, Shenyi Lian, Wenqi Bai, Weijing Cai, Yanan Yang, Bo Su, Yanfeng Xi, Dongmei Lin
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-08-01
Series:Cancer Biology & Medicine
Subjects:
microsatellite instability
mismatch repair
sequencing
lynch syndrome
somatic genetic characteristics
Online Access:https://www.cancerbiomed.org/content/19/8/1235

Internet

https://www.cancerbiomed.org/content/19/8/1235

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