Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study

Cell free DNA (cfDNA) and circulating tumor cell free DNA (ctDNA) from blood (plasma) are increasingly being used in oncology for diagnosis, monitoring response, identifying cancer causing mutations and detecting recurrences. Circulating tumor RB1 DNA (ctDNA) is found in the blood (plasma) of retino...

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Main Authors: David H. Abramson, Diana L. Mandelker, A. Rose Brannon, Ira J. Dunkel, Ryma Benayed, Michael F. Berger, Maria E. Arcila, Marc Ladanyi, Danielle Novetsky Friedman, Gowtham Jayakumaran, Monica S. Diosdado, Melissa A. Robbins, Dianna Haggag-Lindgren, Neerav Shukla, Michael F. Walsh, Prachi Kothari, Dana W. Y. Tsui, Jasmine H. Francis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897525/?tool=EBI