Pharmacokinetic study on the interaction between succinic acid and irbesartan in rats and its potential mechanism

Context Succinic acid and irbesartan are commonly used drugs in cardiovascular disease treatment. The interaction might occur during their co-administration, which was still unclear. Objective To reveal the effect of succinic acid on the metabolism of irbesartan and its potential mechanism. Material...

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Bibliographic Details
Main Authors: Yongpeng Wang, Ruping Rui, Xiaoyan Zhang, Bin Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2021.2002370