Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity

Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity

Abstract Background MET-driven acquired resistance is emerging with unanticipated frequency in patients relapsing upon molecular therapy treatments. However, the determination of MET amplification remains challenging using both standard and next-generation sequencing-based methodologies. Liquid biop...

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Bibliographic Details
Main Authors: Francesca Bersani, Francesca Picca, Deborah Morena, Luisella Righi, Francesca Napoli, Mariangela Russo, Daniele Oddo, Giuseppe Rospo, Carola Negrino, Barbara Castella, Marco Volante, Angela Listì, Vanessa Zambelli, Federica Benso, Fabrizio Tabbò, Paolo Bironzo, Emanuele Monteleone, Valeria Poli, Filippo Pietrantonio, Federica Di Nicolantonio, Alberto Bardelli, Carola Ponzetto, Silvia Novello, Giorgio V. Scagliotti, Riccardo Taulli
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Circular RNA
Biomarker
Receptor tyrosine kinase
Molecular-targeted therapy resistance
Online Access:https://doi.org/10.1186/s13046-023-02690-5

Internet

https://doi.org/10.1186/s13046-023-02690-5

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