IKK-mediated CYLD phosphorylation and cellular redox activity
Abstract Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the...
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Format: | Article |
Language: | English |
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BMC
2022-02-01
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Series: | Molecular Medicine |
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Online Access: | https://doi.org/10.1186/s10020-022-00439-y |