IKK-mediated CYLD phosphorylation and cellular redox activity

Abstract Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the...

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Bibliographic Details
Main Author: Adnan Erol
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-022-00439-y