Genetically predicted telomere length and its relationship with neurodegenerative diseases and life expectancy

Telomere length (TL) is a biomarker of biological aging. Shorter telomeres have been associated with mortality and increased rates of age-related diseases. However, observational studies are unable to conclude whether TL is causally associated with those outcomes. Mendelian randomization (MR) was de...

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Bibliographic Details
Main Authors: Blanca Rodríguez-Fernández, Juan Domingo Gispert, Roderic Guigo, Arcadi Navarro, Natalia Vilor-Tejedor, Marta Crous-Bou
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022003397