Analgesic Effect of Tramadol Is not Altered by Postoperative Systemic Inflammation after Major Abdominal Surgery

Analgesic Effect of Tramadol Is not Altered by Postoperative Systemic Inflammation after Major Abdominal Surgery

Tramadol is a commonly used analgesic in intensive care units (ICUs) for acute postoperative pain. Conversion of tramadol into active metabolites may be impaired in inflammatory states. Catechol-O-methyltransferase may influence pain. The aim of the study was to examine differences in the analges...

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Bibliographic Details
Main Authors: Nenad Nešković, Saška Marczi, Dario Mandić, Boris Mraovic, Sonja Škiljić, Gordana Kristek, Hrvoje Vinković, Slavica Kvolik
Format: Article
Language:English
Published: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2021-01-01
Series:Acta Clinica Croatica
Subjects:
Analgesia
Critical care
Systemic inflammatory response
Catechol-O-methyltransferase
Tramadol
Online Access:https://hrcak.srce.hr/file/383174

Internet

https://hrcak.srce.hr/file/383174

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