Identification of missed viruses by metagenomic sequencing of clinical respiratory samples from Kenya

Abstract Pneumonia remains a major cause of mortality and morbidity. Most molecular diagnoses of viruses rely on polymerase chain reaction (PCR) assays that however can fail due to primer mismatch. We investigated the performance of routine virus diagnostics in Kilifi, Kenya, using random-primed vir...

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Bibliographic Details
Main Authors: My V. T. Phan, Charles N. Agoti, Patrick K. Munywoki, Grieven P. Otieno, Mwanajuma Ngama, Paul Kellam, Matthew Cotten, D. James Nokes
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03987-1