Calcium oxalate crystals trigger epithelial-mesenchymal transition and carcinogenic features in renal cells: a crossroad between kidney stone disease and renal cancer

Calcium oxalate crystals trigger epithelial-mesenchymal transition and carcinogenic features in renal cells: a crossroad between kidney stone disease and renal cancer

Abstract Increasing evidence of association between kidney stone disease (KSD) and renal cell carcinoma (RCC) has been reported. Nevertheless, mechanism underlying such association remained unknown. Herein, we investigated the effects of calcium oxalate monohydrate (COM), a major crystalline compone...

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Bibliographic Details
Main Authors: Paleerath Peerapen, Wanida Boonmark, Pattaranit Putpeerawit, Visith Thongboonkerd
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Experimental Hematology & Oncology
Subjects:
ARID1A
Carcinogenesis
EMT
PTEN
RCC
TPX2
Online Access:https://doi.org/10.1186/s40164-022-00320-y

Internet

https://doi.org/10.1186/s40164-022-00320-y

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