Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer

Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer

Summary: Triple-negative breast cancer (TNBC) is the most elusive subtype of breast cancer that encounters treatment dilemmas owing to the paucity of druggable targets. We found hyperactivation of c-MET and ephrin type-A receptor 2 (EphA2) in patients treated with 5FU driven chemotherapy which corre...

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Bibliographic Details
Main Authors: Debarpan Mitra, Depanwita Saha, Gaurav Das, Rimi Mukherjee, Samir Banerjee, Neyaz Alam, Saunak Mitra Mustafi, Partha Nath, Anuj Majumder, Biswanath Majumder, Nabendu Murmu
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Phytopharmacy
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223024720

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223024720

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