Unveiling potent Schiff base derivatives with selective xanthine oxidase inhibition: In silico and in vitro approach

Unveiling potent Schiff base derivatives with selective xanthine oxidase inhibition: In silico and in vitro approach

This research describes the synthesis by an environmentally-friendly method, microwave irradiation, development and analysis of three novel and one previously identified Schiff base derivative as a potential inhibitor of bovine xanthine oxidase (BXO), a key enzyme implicated in the progression of go...

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Bibliographic Details
Main Authors: Fatna Bellahcene, Khedidja Benarous, Arif Mermer, Houssem Boulebd, Talia Serseg, Abderahmane Linani, Alaeddine Kaouka, Mohamed Yousfi, Asad Syed, Abdallah M. Elgorban, Yasuhiro Ozeki, Sarkar M.A. Kawsar
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Saudi Pharmaceutical Journal
Subjects:
Schiff base
Triazole
Gout
Xanthine oxidase inhibition
In silico approach
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016424001129

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http://www.sciencedirect.com/science/article/pii/S1319016424001129

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