Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies

Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies

Autoantibodies (Abs) are biomarkers for many disease conditions and are increasingly used to facilitate diagnosis and treatment decisions. To guarantee high sensitivity and specificity, the choice of their detection method is crucial. Via cell-based assays, we recently found 21 patients with neurolo...

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Bibliographic Details
Main Authors: Christian P. Moritz, Le-Duy Do, Yannick Tholance, Pierre-Baptiste Vallayer, Véronique Rogemond, Bastien Joubert, Karine Ferraud, Coralie La Marca, Jean-Philippe Camdessanché, Jérôme Honnorat, Jean-Christophe Antoine
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
argonaute antibodies
sensory neuronopathy
ganglionopathie
Anti-Su antibodies
autoimmune neuropathy
conformation-stabilizing ELISA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.972161/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.972161/full

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