3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors

3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors

Abstract In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule 3-oxo-C12:2-HSL, first identified in human gut microbiota, exerts anti-inflammatory effects and could play a role in inflammatory bowe...

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Bibliographic Details
Main Authors: Garance Coquant, Doriane Aguanno, Loïc Brot, Christine Belloir, Julie Delugeard, Nathalie Roger, Hang-Phuong Pham, Loïc Briand, Marielle Moreau, Luisa de Sordi, Véronique Carrière, Jean-Pierre Grill, Sophie Thenet, Philippe Seksik
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13451-3

Internet

https://doi.org/10.1038/s41598-022-13451-3

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