Chromatin condensation retains the osteogenic transcription factor, RUNX2, in the nucleus of human mesenchymal stem cells
Mechanical forces transduced to the nucleus that affect intranuclear organization are critical regulators for directing the differentiation of mesenchymal stem cells (MSCs). The supraphysiological dose of a mechanical cue, which is from the stiff surface of the substrate like standard tissue culture...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Japan Society of Mechanical Engineers
2020-05-01
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| Series: | Journal of Biomechanical Science and Engineering |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jbse/15/2/15_20-00083/_pdf/-char/en |