Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode <i>Litomosoides sigmodontis</i>

Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode <i>Litomosoides sigmodontis</i>

More than two-hundred-million people are infected with filariae worldwide. However, there is no vaccine available that confers long-lasting protection against filarial infections. Previous studies indicated that vaccination with irradiated infective L3 larvae reduces the worm load. This present stud...

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Bibliographic Details
Main Authors: Johanna F. Scheunemann, Frederic Risch, Julia J. Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J. Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Vaccines
Subjects:
filariae
<i>Litomosoides sigmodontis</i>
3pRNA
poly(I:C)
vaccination
nucleic acid receptor
Online Access:https://www.mdpi.com/2076-393X/11/5/966

Internet

https://www.mdpi.com/2076-393X/11/5/966

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