100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB

100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB

Abstract Background Gene duplication has led to a most remarkable adaptation involved in vertebrates’ host-pathogen arms-race, the major histocompatibility complex (MHC). However, MHC duplication history is as yet poorly understood in non-mammalian vertebrates, including birds. Results Here, we prov...

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Bibliographic Details
Main Authors: Julien Goebel, Marta Promerová, Francesco Bonadonna, Karen D. McCoy, Céline Serbielle, Maria Strandh, Glenn Yannic, Reto Burri, Luca Fumagalli
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Genomics
Subjects:
Birds
Birth-death evolution
Concerted evolution
Gene duplication
Gene conversion
Major histocompatibility complex
Online Access:http://link.springer.com/article/10.1186/s12864-017-3839-7

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http://link.springer.com/article/10.1186/s12864-017-3839-7

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