Clinical and Genetic Risk Factors for Drug-Induced Liver Injury Associated with Anti-Tuberculosis Treatment—A Study from Patients of Portuguese Health Centers

Clinical and Genetic Risk Factors for Drug-Induced Liver Injury Associated with Anti-Tuberculosis Treatment—A Study from Patients of Portuguese Health Centers

Drug-induced liver injury (DILI) is an unpredictable and feared side effect of antituberculosis treatment (AT). The present study aimed to identify clinical and genetic variables associated with susceptibility to AT-associated hepatotoxicity in patients with pulmonary tuberculosis treated with a sta...

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Bibliographic Details
Main Authors: Maria João Cavaco, Celeste Alcobia, Bárbara Oliveiros, Luís Alcides Mesquita, Aurora Carvalho, Fernando Matos, José Miguel Carvalho, Miguel Villar, Raquel Duarte, João Mendes, Carolina Ribeiro, Carlos Robalo Cordeiro, Fernando Regateiro, Henriqueta Coimbra Silva
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Personalized Medicine
Subjects:
tuberculosis
DILI
NAT2
ABCB11
isoniazid
RUCAM
Online Access:https://www.mdpi.com/2075-4426/12/5/790

Internet

https://www.mdpi.com/2075-4426/12/5/790

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