The Role of <i>TP53</i> in Adaptation and Evolution

The <i>TP53</i> gene is a major player in cancer formation, and it is considered the most important tumor suppressor gene. The p53 protein acts as a transcription factor, and it is involved in DNA repair, senescence, cell-cycle control, autophagy, and apoptosis. Beyond cancer, there is e...

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Bibliographic Details
Main Authors: Konstantinos Voskarides, Nefeli Giannopoulou
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/3/512