Early Events of the Reaction Elicited by CSF-470 Melanoma Vaccine Plus Adjuvants: An In Vitro Analysis of Immune Recruitment and Cytokine Release

Early Events of the Reaction Elicited by CSF-470 Melanoma Vaccine Plus Adjuvants: An In Vitro Analysis of Immune Recruitment and Cytokine Release

In a previous work, we showed that CSF-470 vaccine plus bacillus Calmette–Guerin (BCG) and granulocyte macrophage colony-stimulating factor (GM-CSF) as adjuvants resulted in a significant benefit in the distant metastasis-free survival when comparing vaccinated vs. IFN-α2b-treated high-risk cutaneou...

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Bibliographic Details
Main Authors: María B. Pampena, María M. Barrio, Estefanía P. Juliá, Paula A. Blanco, Erika M. von Euw, José Mordoh, Estrella Mariel Levy
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
immunotherapy
melanoma vaccine
innate immunity
leukocyte recruitment
pro-inflammatory cytokines
bacillus Calmette–Guerin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01342/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01342/full

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