PBS-1086, a Rel Inhibitor of NF-κB, Ameliorates Collagen-Induced Arthritis in Mice

The family of nuclear factor-kappaB (NF-κB) transcription factors is intimately involved in the regulation of expression of numerous genes in the setting of the inflammatory response. Inflammation, cartilage degradation, cell proliferation, angiogenesis and pannus formation are hallmarks of the path...

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Bibliographic Details
Main Authors: D. Impellizzeri, E. Mazzon, R. Di Paola, M. Galuppo, P. Bramanti, J. Zhang, K. Bobb, D. Monie, J. Meshulam, D.R. Sliskovic, S. Cuzzocrea
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1201000106