Common Variants in Osteopontin and <i>CD44</i> Genes as Predictors of Treatment Outcome in Radiotherapy and Chemoradiotherapy for Non-Small Cell Lung Cancer

Common Variants in Osteopontin and <i>CD44</i> Genes as Predictors of Treatment Outcome in Radiotherapy and Chemoradiotherapy for Non-Small Cell Lung Cancer

Osteopontin (OPN)-CD44 signaling plays an important role in promoting tumor progression and metastasis. In cancer, OPN and CD44 overexpression is a marker of aggressive disease and poor prognosis, and correlates with therapy resistance. In this study, we aimed to evaluate the association of single n...

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Bibliographic Details
Main Authors: Seweryn Gałecki, Agnieszka Gdowicz-Kłosok, Regina Deja, Barbara Masłyk, Monika Giglok, Rafał Suwiński, Dorota Butkiewicz
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
osteopontin
OPN
SPP1
CD44
lung cancer
polymorphism
Online Access:https://www.mdpi.com/2073-4409/12/23/2721

Internet

https://www.mdpi.com/2073-4409/12/23/2721

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