Niclosamide from an anthelmintic drug to a promising adjuvant therapy for diabetic kidney disease: randomized clinical trial

Abstract Background Diabetic kidney disease (DKD) is a serious complication that begins with albuminuria and often leads to a rapid progressive decline in renal function. Niclosamide is a potent inhibitor of the Wnt/β-catenin pathway, which controls the expression of multiple genes of the renin–angi...

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Bibliographic Details
Main Authors: Basma Mahrous El-fatatry, Sahar Mohamed El-Haggar, Osama Mohamed Ibrahim, Khaled Hamed Shalaby
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-023-00995-1