Typical response of CD14++CD16– monocyte to knee synovial derived mediators as a key target to overcome the onset and progression of osteoarthritis

Typical response of CD14++CD16– monocyte to knee synovial derived mediators as a key target to overcome the onset and progression of osteoarthritis

ObjectiveSynovitis with increased infiltration of immune cells is observed in osteoarthritis (OA). Given the inflammatory condition of synovitis, we explored the protein profile of OA synovium (OAS) and its effect on circulating monocytes activation, migration, and functional commitments.MethodsKnee...

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Bibliografische gegevens
Hoofdauteurs: Nik Syazana Izyan Saffery, Krishnamurithy Genasan, Chee Ken Chan, Khairul Anwar Ayob, Seow Hui Teo, Mohamed Zubair Mohamed Al-Fayyadh, Iekhsan Othman, Syafiq Asnawi Zainal Abidin, Murali Malliga Raman, Hanumantha Rao Balaji Raghavendran, Tunku Kamarul
Formaat: Artikel
Taal:English
Gepubliceerd in: Frontiers Media S.A. 2022-08-01
Reeks:Frontiers in Medicine
Onderwerpen:
osteoarthritis
synovium
inflammation
MALDI-imaging
proteomics
monocytes
Online toegang:https://www.frontiersin.org/articles/10.3389/fmed.2022.904721/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.904721/full

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