Ameliorative Effect of Structurally Divergent Oleanane Triterpenoid, 3-Epifriedelinol from <i>Ipomoea batatas</i> against BPA-Induced Gonadotoxicity by Targeting PARP and NF-κB Signaling in Rats

Ameliorative Effect of Structurally Divergent Oleanane Triterpenoid, 3-Epifriedelinol from <i>Ipomoea batatas</i> against BPA-Induced Gonadotoxicity by Targeting PARP and NF-κB Signaling in Rats

The pentacyclic triterpenoids (PTs) of plant origin are reputed to restrain prostate cancer (PCa) cell proliferation. This study aims to assess 3-epifriedelinol (EFD) isolated from aerial part of Ipomoea batatas against PCa and its potential mechanism, in vitro and in vivo. Molecular docking affirms...

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Bibliographic Details
Main Authors: Muhammad Majid, Anam Farhan, Muhammad Waleed Baig, Muhammad Tariq Khan, Yousaf Kamal, Syed Shams ul Hassan, Simona Bungau, Ihsan-ul Haq
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
<i>Ipomoea</i>
aerial part
sweet potato
inflammation
prostate
antiproliferative
Online Access:https://www.mdpi.com/1420-3049/28/1/290

Internet

https://www.mdpi.com/1420-3049/28/1/290

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