Developmental modeling of hepatogenesis using obese iPSCs-hepatocyte differentiation uncovers pathological features

Abstract Obesity is a multigene disorder. However, in addition to genetic factors, environmental determinants also participate in developing obesity and related pathologies. Thus, obesity could be best described as a combination of genetic and environmental perturbations often having its origin duri...

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Bibliographic Details
Main Authors: Divya Saro Varghese, Thilina T. Alawathugoda, Muhammad Abid Sheikh, Anil Kumar Challagandla, Bright Starling Emerald, Suraiya A. Ansari
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05125-9