Developmental modeling of hepatogenesis using obese iPSCs-hepatocyte differentiation uncovers pathological features
Abstract Obesity is a multigene disorder. However, in addition to genetic factors, environmental determinants also participate in developing obesity and related pathologies. Thus, obesity could be best described as a combination of genetic and environmental perturbations often having its origin duri...
Main Authors: | Divya Saro Varghese, Thilina T. Alawathugoda, Muhammad Abid Sheikh, Anil Kumar Challagandla, Bright Starling Emerald, Suraiya A. Ansari |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05125-9 |
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